Recombinant SARS-Cov-2 Spike S1 protein (N501Y, K417N, E484K), His (HEK293)
重组SARS冠状病毒2 Spike突变蛋白S1(N501Y, K417N, E484K) His tag
| 英文名称 | Recombinant SARS-Cov-2 Spike S1 protein (N501Y, K417N, E484K), His (HEK293) |
| 中文名称 | 重组SARS冠状病毒2 Spike突变蛋白S1(N501Y, K417N, E484K) His tag |
| 别 名 | SARS-CoV-2 spike protein; 2019-nCOV Spike protein; Spike glycoprotein; Spike protein ; Surface glycoprotein; SPIKE_SARS2; 2019-nCOV Spike protein S1(N501Y, K417N, E484K), Recombinant (His Tag); Recombinant SARS-COV-2 Spike S1 (N501Y, K417N, E484K) . ;Recombinant SARS-Cov-2 Spike S1 protein (N501Y, K417N, E484K), His (HEK293) 突变型新冠蛋白; 新冠病毒S蛋白突变体（N501Y, K417N, E484K）; 重组新冠病毒 Spike突变蛋白S(N501Y, K417N, E484K); 新型冠状病毒Spike突变体蛋白; |
| 理论分子量 | 73kDa |
| 检测分子量 | 120-140 kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | ＞0.5 mg/ml |
| 物 种 | SARS-Cov-2 |
| 序 列 | 16-685/1273 |
| 纯 度 | >95% as determined by SDS-PAGE |
| 纯化方法 | AC |
| 内毒素 | Not analyzed |
| 表达系统 | HEK293 cell |
| 活性 | Yes |
| 标签 | His |
| 缓 冲 液 | Lyophilized from 0.22 um filtered solution in 2X PBS (pH=7.4). Normally 5% trehalose is added as protectant before lyophilization. |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 | SARS-CoV-2 exploits angiotensin-converting enzyme 2 (ACE2) as a receptor to invade cells. It has been reported that the UK and South African strains may have higher transmission capabilities, eventually in part due to amino acid substitutions on the SARS-CoV-2 Spike protein.The results of a study show the N501Y replacement in this region of the interface (present in both the UK and South African strains) should be favorable for the interaction with ACE2, while the K417N and E484K substitutions (South African strain) would seem neutral or even unfavorable |
本产品仅供科研使用.请勿用于医药,不能用于临床治疗诊断使用！