Recombinant Murine KC/CXCL1-自主发布-资讯-生物在线

Recombinant Murine KC/CXCL1

作者:北京百奥创新科技有限公司 2023-03-09T13:56 (访问量:458)

SpeciesGene IDAccessionSourceLengthMWTag
Mouse14825P12850E. coli72aa7.8kDa
About this Antibody
NameRecombinant Murine KC/CXCL1 (Recombinant Murine KC/CXCL1; rMuKC/CXCL1);Recombinant Mouse KC/CXCL1 ; 重组小鼠角质形成细胞衍生趋化因子/CXCL1
SynonymsCINC-1; GRO alpha; KC; MGSA-alpha
Purity>97% by SDS-PAGE and HPLC analyses.
Biological ActivityFully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood neutrophils is in a concentration range of 10-100ng/ml.
Physical AppearanceSterile Filtered White lyophilized (freeze-dried) powder.
FormulationLyophilized from a 0.2μm filtered concentrated solution in PBS, pH7.4.
EndotoxinLess than 1EU/μg of rMuKC/CXCL1 as determined by LAL method.
ReconstitutionWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.
CategoryChemokines
BackgroundMurine CXCL1, also known as KC, is belonging to the CXC chemokine family. It is encoded by the GRO gene now designated CXCL1. The gene for CXCL1 was initially discovered in mouse fibroblasts by plateletderived growth factor. KC is member of the intercrine alpha (chemokine C-X-C) subfamily of chemokines. It is secreted by human melanoma cells, and also expressed by macrophages, neutrophils and epithelial cells. The functional receptor for CXCL1 has been identified as CXCR2. CXCL1 has chemotactic activity for neutrophils, and plays a role in inflammation and wound healing. Amino acid sequence of murine CXCL1 is approximately 60% identical to the human CXCL1. KC was found to be involved in monocyte arrest on atherosclerotic endothelium and may also play a pathophysiological role in Alzheimer's disease.
Amino Acid SequenceAPIANELRCQ CLQTMAGIHL KNIQSLKVLP SGPHCTQTEV IATLKNGREA CLDPEAPLVQ KIVQKMLKGV PK

包装清单:

产品编号产品名称包装
P6708-5μgRecombinant Murine KC/CXCL15μg
P6708-20μgRecombinant Murine KC/CXCL120μg
P6708-100μgRecombinant Murine KC/CXCL1100μg
P6708-1mgRecombinant Murine KC/CXCL11mg
-说明书1份

保存条件:
-20℃或更低温度保存,至少一年有效。由于蛋白的每次冻融均会引起部分失活,所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液),须分装后-20℃或更低温度冻存,以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
为了您的安全和健康,请穿实验服并戴一次性手套操作。

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