Recombinant mouse ABCB11 protein
重组小鼠胆汁酸盐输出泵/ATP结合盒转运蛋白11
| 英文名称 | Recombinant mouse ABCB11 protein |
| 中文名称 | 重组小鼠胆汁酸盐输出泵/ATP结合盒转运蛋白11 |
| 别 名 | ABC member 16, MDR/TAP subfamily; ABCBB_HUMAN; ATP binding cassette sub family B (MDR/TAP) member 11; ATP binding cassette sub family B member 11; ATP-binding cassette sub-family B member 11; Bile salt export pump; BRIC2; Bsep; PGY4; progressive familial intrahepatic cholestasis 2; Sister of P glycoprotein; Spgp. |
| 理论分子量 | 15kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | >1mg/ml |
| 物 种 | Mouse |
| 序 列 | 616-750/1321 |
| 纯 度 | >90% as determined by SDS-PAGE |
| 纯化方法 | AC |
| 内毒素 | Not analyzed |
| 表达系统 | E.coli |
| 活性 | Not tested |
| 标签 | His Tag |
| 缓 冲 液 | 20mM Tris-Hcl(pH=8.0) |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 | ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of proteins that catalyze the transport of molecules across extra- and intracellular membranes through the energy of ATP hydrolysis. ABC genes comprise seven subfamilies, designated ABC1, Mdr/TAP, MRP, ALD, OABP, GCN20 and White. The secretion of bile salt molecules from blood into bile is a major driving force for bile formation. Bile salt export pump (BSEP) is a member of the Mdr/TAP subfamily of ABC transporters that mediates the transport of bile acids across the hepatocyte canalicular membrane and regulates bile acid-dependent bile secretion. BSEP contains putative phosphorylation sites for protein kinase A, protein kinase C (PKC) and Ca2+-calmodulin dependent kinase II, whose regulation may be dependent on bile salt concentration. |
| 产品图片 |
 The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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本产品仅供科研使用.请勿用于医药,不能用于临床治疗诊断使用！