Monoclonal Antibody against Ubiquitin (3-39)-抗体-抗体-生物在线
翌圣生物科技(上海)股份有限公司
Monoclonal Antibody against Ubiquitin (3-39)

Monoclonal Antibody against Ubiquitin (3-39)

商家询价

产品名称: Monoclonal Antibody against Ubiquitin (3-39)

英文名称: Monoclonal Antibody against Ubiquitin (3-39)

产品编号: SIG-39500

产品价格: null

产品产地: USA

品牌商标: COVANCE

更新时间: 2023-08-17T13:40:59

使用范围:

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Description Ubiquitin (3-39) Monoclonal Antibody  (SIGNET) - SIGNET ANTIBODIES Monoclonal Antibody against Ubiquitin (3-39)
(Formerly Signet Catalog Nos: 9500-02, 9500-05, 9500-10)
Intended Use **Research Use Only (RUO)**

This product is sold for laboratory research use only, not for human or in-vivo use.
Clone 3-39
Form Ascites
Host Mouse
IsoType IgG1, kappa
[Ab] Ubiquitin (3-39) Monoclonal Antibody  (SIGNET) - SIGNET ANTIBODIES ~2 mg/mL
Specificity Ubiquitin (3-39) Monoclonal Antibody  (SIGNET) - SIGNET ANTIBODIES This antibody detects ubiquitinated proteins. It is specific for residues 50-65 of ubiquitin and recognizes ubiquitinated protein, but not free ubiquitin. Clone 3-39 can be used on native or detergent extracted formalin fixed tissues and the epitope is resistant to proteolytic enzyme treatment.
Uses Ubiquitin (3-39) Monoclonal Antibody  (SIGNET) - SIGNET ANTIBODIES This antibody is effective in immunoblotting, immunohistochemistry (IHC) on unfixed tissues, immunoprecipitation (IP) and ELISA.
Suggested Working Dilution Ubiquitin (3-39) Monoclonal Antibody  (SIGNET) - SIGNET ANTIBODIES The optimal working dilution should be determined for each specific assay condition.
  • Western blot: 1:1,000
  • IHC: 1:100 - 1:1,000
  • IP: 1:100
  • ELISA: 1:10,000
Storage Ubiquitin (3-39) Monoclonal Antibody  (SIGNET) - SIGNET ANTIBODIES Store at -20°C or below. Upon initial thawing, apportion into working aliquots and store at -20°C or below. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody. Do not store in frost-free freezers.
References Wang GP, Khatoon S, Iqbal K, Grundke-Iqbal I. Brain ubiquitin is markedly elevated in Alzheimer’s disease. Brain Res 566:146- 151, 1991.

Wang GP, Iqbal K, Bucht G, Winblad B, Wisniewski HM, Grundke- Iqbal I. Alzheimer’s disease: paired helical filament immunoreactivity in cerebrospinal fluid. Acta Neuropathol 82:6-12, 1991.

Perry G, Mulvhill P, Fried VA, Smith HT, Grundke-Iqbal I, Iqbal K. Immunochemical properties of ubiquitin conjugated in the paired helical filaments of Alzheimer’s disease. J Neurochem 52:1523- 1528, 1989.

Galloway PG, Grundke-Iqbal I, Iqbal K, Perry G. Lewy bodies contain epitopes both shared and distinct from Alzheimer neurofibrillary tangles. J Neuropath Exper Neurol 47:654-663, 1988.

Grundke-Iqbal I, Iqbal K, Quinlan M, Tung YC, Zaidi M, Wisniewski HM. Microtubule-associated protein tau, a component of Alzheimer paired helical filaments. J Biol Chem 261:6084-6089, 1986.

Grundke-Iqbal I, Wang GP, Iqbal K, Tung YC, Wisniewski HM. Alzheimer paired helical filaments: Identification of polypeptides with monoclonal antibodies. Acta Neuropathol 68:279-283, 1985.

Wang GP, Grundke-Iqbal, Kascsak RJ, Iqbal K, Wisniewski HM. Alzheimer neurofibrillary tangles: Monoclonal antibodies to inherent antigen(s). Acta Neuropathol 62:268-275, 1984.
Warranty/Conditions Ubiquitin (3-39) Monoclonal Antibody  (SIGNET) - SIGNET ANTIBODIES Covance products may not be resold or modified for resale without prior written approval.
Rev. Date Ubiquitin (3-39) Monoclonal Antibody  (SIGNET) - SIGNET ANTIBODIES 4/8/2007