Anti-SHANK1/SHANK3 mAb: Alkaline Phosphatase [S367-51]
产品名称: Anti-SHANK1/SHANK3 mAb: Alkaline Phosphatase [S367-51]
英文名称: SHANK1/SHANK3 Monoclonal Antibody: Alkaline Phosphatase [S367-51]
产品编号: SMC-460D-ALP
产品价格: null
产品产地: 加拿大
品牌商标: StressMarq
更新时间: null
使用范围: WB, ICC, IHC
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SHANK proteins are scaffolding adaptors that have been shown to integrate neurotransmitter receptors into the cortical cytoskeleton at postsynaptic densities. SHANK1-3 of the SHANK/ProSAP family are molecular scaffolds in the postsynaptic density (PSD). SHANK recruits betaPIX and PAK to dendritic spines to regulate postsynaptic structure and interacts with ionotropic receptor and metabotropic glutamate receptor complexes. Transcript splice variation in the Shank family influences the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain to ensure normal development.