SUR1 and SUR2B 单克隆抗体: ATTO 488-抗体-抗体-生物在线
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SUR1 and SUR2B 单克隆抗体: ATTO 488

SUR1 and SUR2B 单克隆抗体: ATTO 488

商家询价

产品名称: SUR1 and SUR2B 单克隆抗体: ATTO 488

英文名称: SUR1 and SUR2B Monoclonal Antibody: ATTO 488 [S323A-31]

产品编号: SMC-432D-A488

产品价格: null

产品产地: 加拿大

品牌商标: StressMarq

更新时间: null

使用范围: WB, ICC

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Sulfonylurea receptors (SUR) are membrane proteins which are the molecular targets of the sulfonylurea class
of antidiabetic drugs whose mechanism of action is to
promote insulin release from pancreatic beta cells. More
specifically, SUR proteins are subunits of the inward-rectifier potassium ion channels Kir6.x (6.1 and 6.2) (1).
The association of four K
ir6.x and four SUR subunits form
an ion conducting channel commonly referred to as the
K
ATP channel.The primary function of the sulfonylurea receptor is to sense
intracellular levels of the nucleotides ATP and ADP and in
response facilitate the open or closing its associated Kir
6.x
potassium channel. Hence the K
ATP
channel monitors the
energy balance within the cell (2).