RBPJ 抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
RBPJ 抗体

RBPJ 抗体

商家询价

产品名称： RBPJ 抗体

英文名称： RBPJ Antibody

产品编号： XY 14613-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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 RBPJ 抗体Applications

In-house applications ELISA, WB, IHC, IP     Application not tested? Please see our Guarantee.
Published applications WB Publications 1 citations –view here
Species specificity Human, Mouse; other species not tested.
Published Species Human
Images
Prev12NextView more validation data
  • 14613-1-AP;mouse kidney tissuemouse kidney tissue were subjected to SDS PAGE followed by western blot with 14613-1-AP(RBPJ antibody) at dilution of 1:1000
  • 14613-1-AP;human pancreas cancerImmunohistochemical of paraffin-embedded human pancreas cancer using 14613-1-AP(RBPJ antibody) at dilution of 1:100 (under 10x lens)
  • 14613-1-AP;human pancreas cancerImmunohistochemical of paraffin-embedded human pancreas cancer using 14613-1-AP(RBPJ antibody) at dilution of 1:100 (under 40x lens)
  • 14613-1-AP;HEK-293 cellsIP Result of anti-RBPJ (IP:14613-1-AP, 3ug; Detection:14613-1-AP 1:1000) with HEK-293 cells lysate 4500ug.
Positive WB detected in Mouse kidney tissue, HEK-293 cells, HeLa cells, HepG2 cells, human heart tissue, human liver tissue, MCF7 cells, mouse pancreas tissue
Positive IP detected in HEK-293 cells
Positive IHC detected in Human pancreas cancer tissue
Recommended dilution WB : 1:500-1:5000
IP : 1:500-1:5000
IHC : 1:20-1:200
 RBPJ 抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information RBPJ 抗体
Immunogen RBPJ fusion protein ag6206 Full name Recombination signal binding protein for immunoglobulin kappa J region
Calculated molecular
weight		 56 kDa Observed molecular 
weight		 60 kDa
GenBank accession 
number		 BC064976 Gene ID (NCBI) 3516
Gene symbol RBPJ Synonyms CBF 1, CBF1, csl, IGKJRB, IGKJRB1, KBF2, NY-REN-30, RBP J, RBP J kappa, RBP JK, RBPJ, RBPJK, RBPSUH, SUH
Background

RBPJ, also named as IGKJRB, IGKJRB1, RBPJK, RBPSUH, NY-REN-30, CBF-1 and CSL, belongs to the Su(H) family. It is a transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. RBPJ acts as a transcriptional repressor when it is not associated with Notch proteins. It is specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence. RBPJ binds to the Runx3 promoter in the atrioventricular canal in vivo, and inhibition of Notch reduces RUNX3 expression in the cardiac cushion of embryonic hearts. RBPJ 抗体

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