Anti-GFAP R416WT mAb: FITC [S206B-9]
产品名称: Anti-GFAP R416WT mAb: FITC [S206B-9]
英文名称: GFAP R416WT Monoclonal Antibody: FITC [S206B-9]
产品编号: SMC-442D-FITC
产品价格: null
产品产地: 加拿大
品牌商标: StressMarq
更新时间: null
使用范围: WB, ICC, IHC
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The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia.